Toolkit: Tools and resources to combat antimalarial resistance

Are you conducting, analysing and reporting studies on antimalarial drug resistance?

Then this catalogue of tools and resources has been designed for you: we want to make sure that policymakers, healthcare officials, laboratory technicians, researchers, and other stakeholders have easy access to available tools and resources.

The MARC SE-Africa toolkit is a catalogue representing a comprehensive list of 126 curated and collated resources and tools to combat antimalarial resistance, including:

• curated and reviewed web-based applications,

• standard operating procedures, reference manuals,

• literature covering a wide range of topics to aid the fight against antimalarial resistance.

The categories covered include Therapeutic Efficacy Studies (TES) and Individual Therapeutic Efficacy Studies (iTES), which are the WHO-recommended gold standard for assessing the effectiveness of current antimalarial treatments. The resources listed in this catalogue also address molecular marker surveillance, focusing on artemisinin resistance markers and partner drug resistance markers, which are crucial for the early detection of resistance and for tracking the spread and evolution of drug-resistant malaria strains.

The toolkit extends its utility to more tools and resources vital for antimalarial research and intervention. It covers resources to address ex vivo susceptibility testing and an array of laboratory processes such as molecular techniques for PCR correction, diagnostic assessment, data management, drug susceptibility, culturing and synchronisation, and various aspects of sample handling, including preparation, preservation, processing, collection, and pharmacology analysis.

This comprehensive approach ensures that users can access crucial information on diagnostic and exposure assessment as well as microscopy techniques, dissemination and communication, trial administration, coordination, and management training and capacity building emergency and safety protocols, product management, sponsorship and funding, bioinformatic processes, clinical management and safety trial methodology, clinical data collection, informed consent, genomic surveillance, and epidemiology.

In addition to exploring the tools and resources here, you can also access them by clicking on the picture of Moxiebot and find the resources you need by using the chatbot: